Which cells are primarily responsible for producing antibodies?

B cells are primarily responsible for producing antibodies, which are crucial components of the adaptive immune response. When activated by specific antigens, typically with the assistance of Helper T cells, B cells undergo a process of differentiation into plasma cells. These plasma cells are specialized for the production and secretion of antibodies that bind to specific antigens, facilitating their neutralization and marking them for destruction by other immune cells.

The production of antibodies is essential for the adaptive immune system's ability to provide targeted defenses against pathogens. This process enables the body to remember past infections and respond more effectively upon subsequent exposures. In contrast, while Helper T cells play a vital role in assisting the activation of B cells and coordinating the immune response, they do not produce antibodies themselves. Macrophages and dendritic cells are important in antigen presentation and phagocytosis but are not involved in antibody production. This underscores the unique and specialized function of B cells in the immune system.